Natural Factors PQQ-10 Ubiquinol, 60 softgels

PQQ and ubiquinol (CoQ10) are synergistic nutrients that modulate cellular signalling pathways, scavenge oxidative free radicals, and support optimal mitochondrial function. Mitochondrial dysfunction plays a role in a variety of conditions and is thought to be an important factor in age-related decline of cell function.

CoQ10 is well established as a mitochondrial enhancer, which may contribute to the prevention of numerous cardiovascular and neurological conditions. CoQ10 increases the efficiency of mitochondrial ATP production and cellular respiration.

Pyrroloquinoline quinone (PQQ) is a compound known to influence multiple cellular pathways, including the production of nerve growth factor (NGF). Like CoQ10, PQQ has diverse benefits for mitochondrial function. It has been shown to attenuate mitochondrial oxidative stress as well as stimulate mitochondrial biogenesis. It also has neuroprotective properties including protecting against glutamate-induced toxicity, a pathway common in many neurodegenerative diseases. PQQ is considered a novel cofactor with antioxidant and B vitamin-like activity. It is naturally fermented to enhance absorption.

Taken together, PQQ and CoQ10 have shown clinical benefits for cognitive performance, such as improving attention and information processing, providing superior mitochondrial support, and exerting cardioprotective effects.

Main selling features:

• Contains therapeutic amounts of both PQQ and  CoQ10
• PQQ is manufactured using a natural fermentation process to enhance absorption
• PQQ works synergistically with CoQ10 to prevent free radical damage and improve cerebral function
• Non-GMO

How it works:
PQQ and ubiquinol work together to protect against age-related decline and degenerative diseases, specifically those affecting organs with very high energy requirements, such as the brain and heart.

PQQ stimulates nerve growth in the brain, leading to improved memory function. It protects against neurodegenerative diseases by hindering self-oxidizing of the DJ-1 gene, which if left unchecked can lead to Parkinson’s disease. PQQ also prevents aggregation of alpha-synuclein and defends nerve cells from the damaging effects of amyloid-beta protein, compounds linked to Parkinson’s disease and Alzheimer’s disease, respectively.

PQQ and ubiquinol have powerful antioxidant effects. For instance, they are able to hinder oxidative damage to brain cells caused by a lack of oxygen supply to the area following a stroke. These compounds also work effectively to protect neurons by inhibiting the damaging effects of prolonged overstimulation, usually associated with seizures and neurodegenerative diseases.

PQQ may also reduce the damage resulting from an acute heart attack, in addition to protecting the heart muscle against severe oxidative stress by enhancing and preserving mitochondrial function.

Medicinal ingredients:
Each softgel contains:      
Coenzyme Q10 (ubiquinone) .......................................................  200 mg
BioPQQ® (pyrroloquinoline quinone disodium salt)..................... 20 mg
Providing pyrroloquinoline quinone ............................................. 17.65 mg
Vitamin E (as natural d-alpha tocopherol) (Sun-E 900TM)
(from non-GMO sunflower oil)...................................................... 5 IU (3.35 mg AT)

Non-medicinal ingredients
Softgel (gelatin, glycerin, purified water, carob), organic flaxseed oil, yellow beeswax, non-GMO sunflower lecithin. 

Recommended Ault Dose:
1 softgel 1-2 times daily