Natural Factors No Flush Niacin 500 mg, 90 capsules

Natural Factors No Flush Niacin 500 mg, 90 capsules

Natural Factors

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Feature Summary

No Flush Niacin, whose technical name inositol hexaniacinate, has been shown to exert the benefits of niacin without flushing or other side effects. It has been used in Europe for over 30 years to lower cholesterol and improve blood flow.

Inositol hexaniacinate (also referred to as hexanicotinate) is a special form of niacin composed of six nicotinic acid molecules bound to and surrounding one molecule of inositol, an unofficial member of the B vitamin group. Used in Europe to not only to lower cholesterol but also to improve blood flow in the treatment of intermittent claudication (a painful cramp in the calf produced when walking as a result of decreased oxygen supply to the calf muscle) and Raynaud's phenomenon (a painful response of the hands or feet to cold exposure due to constriction of blood vessels supplying the hands).

A recent study in the American Journal of Cardiology showed niacin's effectiveness for raising HDL cholesterol: "In a head-to-head comparison study, niacin 2,000 mg/day increased HDL-C more than gemfibrozil 1,200 mg/day, and decreased the total cholesterol-to-HDL-C ration, lipoprotein(a) and fibrinogen levels significantly more."


Each capsule contains
Niacin (Inositol Hexanicotinate)..................................................500 mg
Inositol (Inositol Hexanicotinate).................................................120 mg

Non-medicinal ingredients
Microcrystalline cellulose, gelatin capsule (gelatin, purified water), vegetable grade magnesium stearate (lubricant). *Niacin delivered in the form of Inositol Hexaniacinate minimizes the side effects associated with other forms of niacin in high doses, such as flushing of the skin and upset stomach


1 capsule daily with meals or as directed by a health care practitioner.


  • Niacin has been shown to potentiate the cholesterol lowering effects of other lipid-lowering drugs, especially the statin drugs like atorvastatin (Lipitor®); gemfibrozil (Lopid®); lovastatin (Mevacor®); pravastin (Pravachol®); simvastatine (Zocor®), etc.
  • Because niacin can impair glucose tolerance, it may interfere with drugs used in the treatment of diabetes. Consult a health care practitioner to discuss proper monitoring of blood sugar levels before taking niacin at therapeutic levels.
  • Inositol hexaniacinate should not be used in patients with pre-existing liver disease or elevation in liver enzymes, gout, or peptic ulcers.

Additional Information

Children: Not be suitable for children unless directed by a health care practitioner.

Pregnancy and Nursing: Considered safe during pregnancy and lactation at dosages below 100 mg. Dosages above 100 mg are not indicated unless directed by a health care practitioner.

Seniors: No special precautions are known.

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